DrMirkin's eZine: Insulin resistance, dhronic constipation, more . . .

Published: Thu, 07/18/24

Updated: Sun, 07/21/24

Dr. Gabe Mirkin's Fitness and Health e-Zine
July 18, 2024
 
Exercise Helps to Treat Insulin Resistance in Diabetics

Up to 70 percent of North American adults will develop diabetes or pre-diabetes, usually from insulin resistance caused by excess fat in the liver and muscles. Exercise helps to empty fat from the liver and muscles, so exercise helps both to prevent and to treat diabetes. A study of 6,718 diabetics, average age 58, followed from 4-96 weeks, found that exercise reduced HBA1c (a blood test that measures cell damage from high blood sugar levels). The more a diabetic exercised, the greater the reduction in HBA1c (Diabetes Care, Jan 2024;47:295–303). The highest level of protection from diabetic cell damage was gained with an average of 244 minutes per week of moderate-intensity aerobic exercise or 157 per week of vigorous exercise (Diabetes Care, 2024;47:196–198).

The American Diabetes Association and the World Health Organization recommend 150 to 300 minutes of moderate exercise or 75–150 minutes of vigorous exercise per week plus strength/resistance training two or more times per week. Many other studies also show that exercise is a major treatment to help prevent the horrible cell damage caused by diabetes.

Definition of Insulin Resistance
Insulin drives sugar, fat and protein from the bloodstream into cells. Insulin resistance means that the cells do not respond to insulin, so sugar accumulates in the bloodstream. Everyone’s blood sugar rises after they eat, and if blood sugar rises too high, sugar irreversibly sticks to cells and can destroy every kind of cell in your body.

To prevent blood sugar from rising too high, your pancreas releases insulin into your bloodstream, which lowers blood sugar by driving sugar from the bloodstream into the liver. However, if the liver is full of fat, it does not accept the sugar and blood sugar levels rise even higher. Insulin resistance can be reversed by emptying fat from the liver, muscles and fat cells. The larger your muscles, the less likely you are to become insulin resistant. High blood sugar causes loss of muscle size (JCI Insight, February 21, 2019;4(4)).

My Recommendations
Almost everyone will benefit from a regular exercise program. By the time people are diagnosed with diabetes, they may have already developed complications such as heart-and-lung blood vessel disease, nerve damage, or kidney and eye diseases (Nat Rev Endocrinol, 2018;14:88–98). Preventing high rises in blood sugar is crucial for lowering these risks. Most cases of diabetes are caused by insulin resistance which usually comes from excess fat in the liver, muscles and fat cells. Both aerobic and resistance exercise help to prevent and treat diabetes by helping to empty the liver and muscles of excess sugar. Exercise also helps to reduce excess weight, high blood pressure, high LDL cholesterol, and high triglycerides, and helps to increase healthy HDL cholesterol and to strengthen muscles and bones.




Ultra-Processed Food: a Common Cause of Constipation

Doctors used 24-hour dietary recalls on 12,716 US adults, of whom 1290 suffered from constipation and 1067 had diarrhea. Those who ate the most ultra-processed foods had more than double the incidence of constipation as those who ate the least, and minimally-processed foods were associated with a markedly reduced incidence of constipation. Substituting 10 percent of ultra-processed foods with minimally processed foods was associated with 10 percent reduced risk for constipation (Clin Gastroenterol Hepatol, May 15, 2024:S1542-3565(24)00448-8). The data was corrected for diet quality and water and fiber intake.

Definitions of Food Processing
Unprocessed foods are usually made from one ingredient (plant or animal) and have undergone either no or almost no changes. Minimally-processed foods are usually a single ingredient but have undergone some processing, such as grinding (flour) or mashing (peanut butter), and may have some added ingredients to improve flavor, texture and shelf life: bread, cheese, pasta and so forth.

Ultra-processed foods are made by removing nutrients such as fiber, vitamins, minerals or antioxidants and adding dyes, preservatives, antioxidants, anticaking agents, flavor enhancers, sugars, fats, salt and other artificial ingredients that are usually designed to make you eat more: sugary drinks, candy, cookies, most breakfast cereals, most fast foods, snack foods and most other foods that come in packages. Food manufacturers know that adding salt and sugar to a food usually makes it taste better so you are more likely to buy their products. More than 75 percent of the North American diet consists of ultra-processed foods.

Chronic Constipation
Constipation is incredibly common in North America, with almost 20 percent of the population suffering from this disorder (Handb Exp Pharmacol, 2017, 239, 59–74). Constipation is generally defined as having fewer than three bowel movements a week, possibly with "a sensation of incomplete evacuation, abdominal bloating, straining, elongated or failed attempts to defecate, hard stools, and necessity of digital disimpaction" (J Clin Med, 2021;10(8):1738).

Lifestyle Changes to Treat Constipation
Our epidemic of constipation is due largely to the food industry that produces mostly ultra-processed foods that contain little or no fiber. People keep looking for constipation cures in a pill, but it is usually curable just with lifestyle changes:
Diet: increase your intake of fiber, found in whole fruits, vegetables, whole grains, beans, nuts and other seeds. Try to avoid or limit refined carbohydrates (foods made from flour and added sugars) and other ultra-processed foods that contain little or no fiber.
Exercise: Try to exercise every day. When you exercise while you have stool in your colon, you will usually develop giant contractions that push stool along your colon.
Hydration: Drink plenty of fluid. Dehydration increases the rate that fluid is absorbed from your colon to make your stool harder. However, treating constipation with increased fluid intake is effective only in dehydrated patients.
Staying regular: Get in the habit of trying to empty your colon at the same time of day every day.

My Recommendations
Eat lots of fiber: fruits, vegetables, whole unground grains, beans, seeds and nuts. I recommend prunes and apples. Try to exercise regularly and keep moving throughout the day.

Diana's Solution: Warm up a cup of your favorite bean or lentil soup (canned Goya brand Black Bean Soup is an easy choice). Stir in a few tablespoons of pecans (about 1/4 cup) that have been chopped up in a nut grinder. Diana says "Eating this every day has completely solved my chronic constipation problem."

Constipation can be caused by serious disease, so if you cannot control constipation with lifestyle changes, check with your doctor for a medical evaluation to try to find a cause and treatment.




Health Benefits of Cutting Back on Processed Meats

A U.S. government health survey estimates that if North Americans reduced their intake of processed meats by 30 percent in the next 10 years, there would be 1.1 million fewer cases of diabetes in the U.S., 382,400 fewer cases of heart disease and 84,400 fewer cases of colon cancer. A 30 percent reduction of mammal meat (1/4 pound per week) would yield 732,000 fewer cases of diabetes, 291,500 fewer cases of heart disease and 32,200 fewer cases of colon cancer (The Lancet Planetary Health Journal, July 3, 2024;8(7):e441-e451). Mammal meat includes beef, pork and lamb; processed meats include bacon, salami, bologna and other deli meats, hot dogs and so forth.

Plant-based diets appear to be more healthful than diets with lots of meat, so entrepreneurs are making foods from plants that look and taste like meat. These foods are highly-processed and may contain sugar, salt, flavor enhancers, preservatives, color enhancers and other additives. See Plant-Based Meat Substitutes May Not Be More Healthful Than Meat. I will continue to follow the research on advantages and disadvantages of these foods.




Donald Sutherland: COPD and Prostate Cancer 

Actor Donald Sutherland died on June 20, 2024, after suffering from prostate cancer and severe lung damage from smoking up to four packs of cigarettes per day. Several years before he died, he stopped smoking and wouldn’t let anyone smoke near him. He kept smokers at least 100 yards away from his movie sets. In his last years, he had to breathe from an oxygen tank all the time.

Sutherland was a Canadian actor and film and television star who, in a 70-year career, won a Prime-time Emmy Award and two Golden Globes, and was an Officer of the Order of Canada. He was voted into the Canadian Walk of Fame in 2000 and the Hollywood Walk of Fame in 2011, and Canada Post issued a stamp in his honor in October 2023. In 2012, he was made a Commandeur of the Ordre des Arts et des Lettres, and in 2019, he received the Companion of the Order of Canada. He starred in many films including The Dirty Dozen (1967), MASH (1970), Kelly’s Heroes (1970), The Eagle Has Landed (1976), Animal House (1978), Pride & Prejudice (2005) and The Hunger Games franchise.

Early Life and Acting Career
Sutherland was born in 1935 in New Brunswick, Canada, and he suffered from rheumatic fever, hepatitis, and poliomyelitis in his childhood. At age 14, he was a news correspondent for local radio station CKBW. In 1957, at age 22, he moved to Britain to study at the London Academy of Music and Dramatic Art, and while there, he appeared in British films and TV. In 1968, at age 33, he went to Hollywood where he starred in many successful films and television productions. In spite of suffering from meningitis and lung damage requiring constant use of oxygen, he continued to be active in movies and television up to 2020. He spent his last years limited by prostate cancer and severe lung disease, and he died of these conditions in 2024. Read more



 
Our Good Food Book is available as an eBook on Amazon for only $0.99
With 100+ of Diana's recipes!



If you like my eZine, please share it with your friends.
Invite them to subscribe at DrMirkin.com



The e-Zine is provided as a service. Dr. Mirkin's reports and opinions are for information only, and are not intended to diagnose or prescribe. For your specific diagnosis and treatment, consult your doctor or health care provider.
For more information visit DrMirkin.com

We DO NOT sell, rent or give your e-mail address to anyone.
Copyright 2024, The Sportsmedicine Institute, Inc.
 
Gabe Mirkin, M.D.

1455 Brier Creek Circle
The Villages FL 32162
USA


Unsubscribe   |   Change Subscriber Options