DrMirkin's eZine: Alcohol, new COVID-19 booster, more . . .
Published: Thu, 04/07/22
April 10, 2022
The World Heart Federation reports that even small amounts of alcohol increase heart attack risk. Taking one drink a day does not help to prevent heart attacks and appears to increase risk for heart attacks (Clinical Nutrition, Feb 1, 2022;41(2):348-355). A study of 371,463 individuals found that no amount of alcohol helps prevent heart disease, even low amounts of alcohol increase heart attack risk, and the more you drink, the greater your chance of suffering a heart attack (JAMA Netw Open, March 2022;5(3):e223849).
Flawed Studies on Health Benefits from Alcohol
The alcoholic beverage industry promotes studies showing that moderate drinkers live slightly longer than non-drinkers, but the non-drinking groups in these studies have included people who gave up alcohol on their doctors' instructions, such as those with high blood pressure, diabetes, high cholesterol, some types of cancer, diseases of the heart, kidney, liver or lungs or other health problems, as well as recovering alcoholics. A study with a 20-year-follow-up of 4,028 18-to-64-year-old German
adults found that when the people who had stopped drinking for medical reasons were removed from the control group, moderate drinkers did not live longer than non-drinkers (PLoS Medicine, Nov 2, 2021;18(11):e1003819).
An analysis of 45 earlier studies showed that those associating moderate drinking of alcohol with reduced heart attack rates were flawed (J Stud Alcohol and Drugs, May 2017;78(3):394-403). To show that moderate drinking is associated with heart attack prevention, researchers must show that nondrinkers have more heart attacks than moderate drinkers. In these studies cited by the alcohol industry, more than half of the people in the "non-drinker" groups were recovering alcoholics or people who had been told to stop drinking because they already suffered from diseases caused in part by drinking or made worse by drinking.
Alcohol and Heart Damage
Drinking any amount of alcohol is associated with increased risk for irregular heartbeats or atrial fibrillation (European Heart J, March 21, 2021;42(12):1170-1177). A study of 79,000 Swedish adults, aged 45-83, followed for up to 12 years, showed that those who drank any amount of wine or liquor daily were at increased risk for atrial fibrillation, an abnormally fast heartbeat that can cause clots, strokes and heart failure (J American College of Cardiology, July 14, 2014).
The more they drank, the more likely they were to develop atrial fibrillation.
People who take just one drink a day are at increased risk for heart disease (J American College of Cardiology, December 5, 2016) and enlarged upper heart and irregular heartbeats that cause clots and strokes (J Am Heart Assoc, Sep 14, 2016;5:e004060; J Am Coll Cardiol, 2016;68(23):2567-2576). Binge drinking, defined as having five or more drinks in a single bout, increased risks even more. Data from six studies including more than 12,500 cases of atrial fibrillation showed that each additional drink per day of any type of alcohol boosted risk of irregular heartbeat by eight percent (J Am Coll Card, July 14, 2014). Many other studies have associated drinking alcohol with atrial fibrillation, high blood pressure, heart failure and strokes. Association is not cause, but I believe that these studies give reason for caution.
Alcohol in any amount has also been linked to increased risk for many types of cancers. See Alcohol At Any Dose Can Increase Cancer Risk
Alcohol and Your Liver
Alcohol can damage every type of cell in your body, and your liver is the only organ that protects you. Your liver breaks down alcohol at a relatively constant rate, but first alcohol is converted to acetaldehyde, which is even more poisonous than alcohol. It can make you feel like throwing up and make your face burn.
Drinking alcohol regularly increases risk for permanent liver damage called cirrhosis (Journal of Hepatology, January 26, 2015). Wine is associated with a lower risk for liver damage than beer or liquor. The authors of this study warn that older drinkers are more likely to have health conditions affected by alcohol or to take medicines that impair their ability to metabolize alcohol.
Definition of a Drink
In all of the studies and reports mentioned here, a “drink” is defined as the amount that takes an average person’s liver one hour to clear half of the alcohol from the bloodstream. However, this can vary with body weight, sex, age, metabolic rate, recent food intake, the type and strength of the alcohol, and any medication you take. Typically, one drink contains 0.6 ounces (14.0 grams or 1.2 tablespoons) of pure alcohol, the amount found in:
• 12 ounces of beer (5% alcohol content)
• 8 ounces of malt liquor (7% alcohol content)
• 5 ounces of wine (12% alcohol content)
• 1.5 ounces of 80-proof liquor (40% alcohol content, e.g., gin, rum, vodka, whiskey)
My Recommendations
Many people have the mistaken belief that it is safe for women to take up to one drink per day and for men to take up to two drinks per day. Almost 30 percent of North Americans drink more than that. The studies I have listed in this article and many more suggest that no amount of alcohol is "safe" or beneficial. Whatever you decide about your own consumption of alcohol, do not base your decision on bad information from the alcoholic beverage industry.
On Tuesday, March 29, 2022, the U.S. Food and Drug Administration authorized a second booster dose of the mRNA vaccines made by Pfizer or Moderna for all adults 50 years and older, to be given at least four months after the first booster of any approved COVID-19 vaccine. At this time, scientists do not have enough data to show that most people need to get this second booster dose. The primary concern is the highly contagious Omicron subvariant known as BA.2, which is now the dominant version of the virus in new U.S. cases (New York Times, March 29, 2022). The research data so far show that a fourth injection offers additional protection for people over 6o and those with conditions that impair their immune systems.
Available Research Data
A study from Israel posted online this week, but not yet reviewed or published, reports that adults over 60 years of age who received a fourth injection were 78 percent less likely to die of COVID-19 than those who got only three injections. However, other studies show that a second booster has very limited benefits for healthy people under sixty and that a fourth dose did not raise antibody titers higher than it did after a third dose. Again, the person who is at high risk for serious disease
is older or has a condition that can impair his immune system.
Who May Need an mRNA Booster Now?
• a fourth injection for those who have received three doses of an mRNA vaccine from Moderna or Pfizer, and are over 60 or have an impaired immune system
• a third injection for those who received one dose of the Johnson & Johnson vaccine and a booster shot of an mRNA vaccine
• a third injection for those who received two doses of the Johnson & Johnson vaccine
Do People Who Have Had COVID-19 Disease Need This Booster?
Most likely, people who have had COVID-19 do not need a fourth injection because the highest and most effective immunity usually comes from having the disease, rather than from receiving the vaccine.
On Thursday, March 18, 2022, University of Pennsylvania swimmer Lia Thomas became the first transgender woman to win an NCAA Division I swimming championship when she won the 500-yard freestyle with a season-best time of 4 minutes, 33.24 seconds. She beat the second-place finisher, Virginia’s Emma Weyant, who finished in 4:34.99.
On February 1, 2022, the sport’s governing body, USA Swimming, adopted an Athlete Inclusion, Competitive Equity and Eligibility Policy, and established a three-person medical panel to administer the policy and review applications for elite and non-elite categories. The new guidelines require female athletes to have at least 36 months of testosterone blood levels below five nanomoles per liter. Read more
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