DrMirkin's eZine: Flat feet, fat in liver, more . . .

Published: Thu, 03/10/22

Dr. Gabe Mirkin's Fitness and Health e-Zine
March 13, 2022
 
Flat Feet, Pigeon Toes and Bow Legs

Many of the world’s great sprinters have flat feet. In the 1964 Tokyo Olympics, Bob Hayes tied the world record when he won the 100 meter dash, and five days later, he ran the anchor leg in the finals of the Olympic 400 meter relay. He took the baton with the US team in fifth place and he passed Jamaica, then Russia, then Poland and then France to run his 100 meters in an incredible 8.6 seconds, the fastest of all time. The next day, several newspapers reported that Hayes was the world’s fastest human in spite of being born with such terrible flat feet that he had to be put in casts to correct them. The newspaper articles should have said that Bob Hayes became the world’s fastest human in spite of ignorant doctors who almost ruined his athletic career by putting him in casts (Cochrane Library, Jan 26, 2022).

Today, most football coaches can pick their halfbacks just by watching them walk. The fastest runners are often flat footed, pigeon toed and bow-legged.
Flat Feet: When you run, you land on the outside bottom of your foot and roll toward the inside. This is called pronation. Most people with flat feet have normal arches, but they appear to be flat only because the ankles roll in excessively causing the arches to roll so far inward that they can touch the ground. This excessive rolling in causes the feet to hit the ground with greater force and therefore cause the heel to move forward faster so that the foot leaves the ground faster and helps the person to run faster (Gait & Posture, October 2008;28(3):405-411).

Pigeon Toes: A tight, strong Achilles tendon in the back of the heel can cause a person to point their toes inward. It also can keep the heel off the ground when you run so you do not have to waste time landing on your heel and then having to raise your heel off the ground. Thus a person with pigeon toes can land on the front part of their feet and immediately step off to their other foot without wasting time landing on their heels.

Bowed Legs: People with bowed legs have knees that whip inward as they step off from one foot to the other, which drives them forward with greater force and helps them to run faster.

Types of Flat Feet: Flexible or Rigid
Between 20 percent and 37 percent of North Americans have some degree of flat feet (J Am Podiatr Med Assoc, May, 1998;88(5):242-8). During World War II, people with flat feet were excused from the armed services draft based on the long-held opinion that flat feet would cause injuries during training and physical activity. However, studies on army recruits showed that those with flat feet had fewer injuries during basic training than those with normal-height arches (Arch Fam Med, July 1993:21:773-7).

The reason for this discrepancy appears to be that there are two different types of flat feet: flexible (also called mobile or pronated) and rigid. The flexible flat foot has a normal arch that appears flat only when the full foot is on the ground. When a person with a flexible flat foot takes his foot off the ground, his arch is clearly visible. The flexible pronated flat foot will have an arch without weight-bearing, which will disappear with weight-bearing. These people with flexible flat feet do not appear to be at increased risk for injuries (Foot & Ankle International, 2002;23(1):43-47). On the other hand, people with rigid flat feet have a flat-appearing arch all the time. Their joints do not allow enough movement to absorb shock and they usually get injured too often to compete in impact sports.

Most flexible pronated flat feet do not need special treatment. In healthy children with painless flexible flat feet, there is little good evidence that special shoes or orthotics help prevent injuries or pain (Cochrane Library, Jan 26, 2022). In competitive collegiate athletes who have flexible pronated flat feet, there is little evidence that orthotics or special shoes help to prevent injuries. The flexible flat foot absorbs the shock of the foot hitting the ground very well, but the rigid flat foot is a very poor shock absorber. People with rigid flat feet usually benefit from using orthotics; special inserts that go in shoes. It is also standard practice for doctors to prescribe orthotics for any flat-footed runner who gets lower leg injuries.

Injuries Associated with High or Low Arches
Runners with high arches are at increased risk for suffering stress fractures, which are small cracks in the bones of their feet and lower legs. If you develop pain in the medial side of your lower leg or your feet, your podiatrist will probably order an MRI to check for a stress fracture. If standard x-rays don't show it and it continues to hurt, you may need to have another x-ray in three weeks to see the callus forming over the crack.

Runners with low arches are at increased risk for knee cap pain (Physician and Sportsmedicine, January 2005). When you run six-minute miles, your foot hits the ground with a force greater than three times body weight. The faster you run, the harder your heel strikes the ground. This force can break bones, damage joints and tear muscles. The human body is designed so you do not land flat-footed when you run. You are supposed to have your foot roll inward when you run to absorb the shock of your foot hitting the ground. The further you roll inward, the greater the protection against this force. The further your foot rolls inward when it strikes the ground, the greater the absorption of the force of your foot striking the ground and the greater the protection from stress fractures. However, when you roll in too much, your lower leg can twist inward excessively, so your kneecap rubs against the long femur bone behind it and causes pain. This is called Runner’s Knee and is often treated with orthotics in your running shoes and special exercises that strengthen your vastus medialis muscle, the muscle on the inside of your upper leg that pulls your knee cap inward.

Barefoot Running Concepts to Help Prevent Injuries
Several years ago, running magazines and books popularized the ancient practice of running barefoot. There is data to show that running barefoot can help to prevent some running injuries (Ex & Sprt Sci Reviews, April 2012;40(2):63–72), even though it markedly increases risk for severe foot trauma from glass or stones. The main function of running shoes is to cushion the force of your feet hitting the ground. This encourages you to take longer strides and the longer your stride, the greater the force of your foot hitting the ground, which can increase the rate of injuries in runners. On the other hand, when you run barefoot, you take shorter strides to protect the skin on your feet. The shorter stride causes you to land further forward on your feet and can protect you from injuries by markedly decreasing the force of your foot hitting the ground.

A study from the University of Wisconsin-La Crosse showed that as people start to feel tired during running, they shorten their strides to decrease the force of their foot striking the ground (Medicine and Science in Sports and Exercise, 1999(December);31(12):1828-33). This lessens the force of their heel striking the ground and places it forward to the area behind the big toe. To compensate for the decreased force of their feet hitting the ground, they move their legs at a faster cadence. You can apply this concept to help you prevent injuries when you run. Shortening your stride will shift your foot strike force forward. You can keep your speed up by increasing your cadence. See Running Injuries from Over-Striding

Note: My son Gene Mirkin, DPM, a practicing podiatrist in Maryland, contributed to this article.




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Excess Fat in Your Liver Increases Risk for Heart Attacks, Strokes and Dementia

A study of 9189 adults between 30 and 75 years of age who were free of cardiovascular disease found that those who had abdominal obesity (storing a large amount of fat in the liver) were at increased risk for dementia, strokes, and heart attacks (JAMA Netw Open, Feb 1, 2022;5(2):e2146324). Many other studies have established that having a fatty liver is associated with:
• increased heart attack risk factors such as high blood sugar, blood pressure, and cholesterol levels (Lancet: Gastroenterology & Hepatology, Sept 20, 2021; J Am Coll Cardiol, 2021;78(5):513-531; J Am Coll Cardiol, 2016;68(14):1509-1521)
• increased risk for heart attacks (Lancet, 2005;366(9497):1640-1649)
• reduced cognitive scores for mental function (J Gerontol A Biol Sci Med Sci, 2009;64(1):103-109).

A review of 36 studies on 5,802,226 middle-aged individuals and 99,668 cases of heart attacks, with a median follow-up period of 6.5 years, found that those with fatty liver disease had 1.5 times the incidence of heart attacks as the general population. The more fat in the liver, the greater the chances of a person suffering and dying from a heart attack.

How Can You Tell If You Have a Fatty Liver?
You can often tell if people have a fatty liver just by looking at them. A person with a big belly and small buttocks is at very high risk because those who store fat primarily in the belly are most likely to also store a large amount of fat in their liver. Many studies show that having excess fat in your liver markedly increases risk for Type II diabetes and heart attacks (JAMA, 2017;317(6):626-634), and also increases all markers of inflammation that are associated with increased risk for heart attacks (Clinical Gastroenterology and Hepatology, February 28, 2019).

If you can pinch more than two inches of fat beneath your skin next to your belly button, the odds are overwhelming that you have too much fat in your liver. At your next routine physical exam, your doctor should order the usual liver function blood tests, but you can still have a fatty liver even if all your liver function tests are normal. Ask your doctor to order a simple sound-wave sonogram of your liver that does not expose you to radiation. The sonogram will show excess fat buildup as white spots in the liver (Nutrition, Metabolism & Cardiovascular Diseases, Dec 30, 2015).

How a Fatty Liver Increases Heart Attack Risk
A high rise in blood sugar after meals causes plaques to form and can also cause plaques to break off to cause a heart attack. Everyone’s blood sugar rises after they eat. To prevent blood sugar from rising too high, your pancreas releases insulin which is supposed to lower high blood sugar levels by driving sugar from the bloodstream into the liver. However, if your liver is full of fat, the excess fat prevents the liver from accepting the sugar and blood sugar levels can rise even higher (Eur J Gastroenterol Hepatol, Dec 2016;28(12):1443-1449). A high rise in blood sugar causes high blood insulin levels that convert blood sugar to a type of fat called triglycerides. Then insulin drives triglycerides into your liver. Having high triglycerides and a fat belly are signs of high blood insulin levels, and high blood levels of insulin constrict arteries to increase the chances of a plaque breaking off.

What Causes a Fatty Liver?
A liver full of fat can be caused by anything that damages the liver. Doctors may separate liver damage into that caused by alcohol and that not caused by alcohol (non-alcoholic fatty liver disease or NAFLD). However, a liver damaged by excess alcohol has the same harmful consequences as a liver damaged by anything else, such as obesity or excess sugar intake (Gastroenterology, May 31, 2019).

Excess Belly Fat Increases Heart Attack Risk Even If You Are Not Overweight
In one study, women with the highest percentage of belly fat had double the risk for heart disease, compared to those with the lowest belly fat (Eur Heart, June 30, 2019). Furthermore, those with the lowest percentage of hip fat and highest percentage of belly fat (apple shape) had three times the risk for heart disease than those with lowest percentage of belly fat and highest percentage of hip fat (pear shape). The researchers concluded that reducing the amount of belly fat by itself would help to reduce heart attack risk significantly, even if the amount of hip fat was not reduced.

Why Sugared Drinks Cause the Highest Rises in Blood Sugar
When you take in liquid sugar, you get a much higher rise in blood sugar than when you take in the same amount of sugar in a solid food. Solid food is not allowed to pass into your intestines because when you eat, the pyloric muscle at the end of the stomach closes and allows only a liquid soup to pass into the intestines. Sugared drinks can pass right through into your intestines, so they cause the quickest rises in blood sugar. Compared to sugar in food, sugared drinks are more tightly associated with increased risk for excess belly fat (Circulation, January 11, 2016; Quart J Med, Apr 26, 2017).

My Recommendations
Fat can be removed from the liver with diet (Diabetologia, 2011 Oct; 54(10): 2506-2514) and with exercise (Scandinavian Journal of Medicine & Science in Sports, March 13, 2017;27(5)).
• If you have a big belly or your blood sugar is greater than 140 one hour after a meal, I recommend that you lose weight (if overweight) with intermittent fasting; check with your doctor.
• Since most liver fat comes from sugar, avoid or severely restrict all sugared drinks and sugar-added foods.
• Restrict other refined carbohydrates such as foods made from flour (bakery products, pasta, many breakfast cereals and so forth).
• Restrict red meat, processed meat and fried foods.
• Eat plenty of vegetables, fruits, seeds and nuts which are rich sources of soluble fiber.
• Try to exercise every day.

Caution: Intense exercise can cause heart attacks in people who already have blocked arteries. Check with your doctor before starting an exercise program or increasing the intensity of your existing program.




John Trojanowski, Dementia Research Pioneer 

Together with his wife, Virginia Man-Yee Lee, researcher John Trojanowski wrote more than 500 scientific papers that made him one of the world’s leading authorities on abnormally-folded proteins that damage the brain:
• tau proteins in Alzheimer disease
• alpha-synuclein in Lewy bodies in Parkinson’s disease
• TDP-43 in Amyotrophic Lateral Sclerosis (ALS) and frontotemporal degeneration.

His colleagues at the University of Pennsylvania said that his scientific contributions were “phenomenal,” because they “combined pathology and biochemistry to figure out what goes wrong, and why, when people get diseases as disparate as Alzheimer’s, Parkinson’s and ALS. The results can lead to improved diagnosis and potential treatments” (New York Times, March 1, 2022).

Early Life and Career in Research
Trojanowski was born on December 17, 1946, the second of seven children, to an Air Force officer father, so he spent his childhood moving from one base to another in the United States and Germany. He was graduated from King’s College in Wilkes-Barre, PA in 1970 and six years later he received a combined MD-PhD degree from Tufts University. He then took a residency at the Massachusetts General Hospital where he met his future wife, Dr. Lee, in a bar. Read more



 
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